Medical Case Reports

Two Unusual cases of Second Cancer-the Worst Nightmare of Cancer Survivor

Background: Second malignancy is one of the late complications of long-term cancer survivors, treated with radiation or chemotherapy.
Methods:  We report two cases of second malignancies here. First, a case of acute promyelocytic leukemia (AML-M3), which developed after 17 months following the completion of treatment with surgery and platinum-based chemoradiation in a patient with carcinoma cervix. Second, a case of Acute Myelomonocytic Leukemia (AML-M4), which developed 10 months after completion of chemotherapy and radiotherapy in a patient with Ewing’s Sarcoma.
Conclusion: The above-mentioned second malignancies are one of the late sequelae of chemoradiation. These two cases are reported here for documentation because of its rarity.

Author(s): Annapoorani Varadarajan, Jyoti Sawhney, Suchita Patel and Dhaval Jetly

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