Abstract

Heart Involvement in Hemoglobinopathies: Two Case Reports and Brief Review of Literature

Τhe two main determinants of cardiovascular phenotype in haemoglobinopathy patients are the underlying molecular defect responsible for the main disease and the therapy applied for its management. The spectrum of cardiovascular manifestations in haemoglobinopathies is wide and includes ventricular dysfunction, pulmonary hypertension, thromboembolic events.

We report a case of thalassemia and one of sickle cell disease having different clinic phenotype with brief literature review.


Author(s):

Wael Yaakoubi*, Manel Ben Hlima, Sana Ouali, Fathia Mghaith and Med Sami Mourali



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