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Undifferentiated Embryonal Sarcoma of Liver- A Rare Case Report

Undifferentiated embryonal sarcoma of liver (USEL) is a rare primary hepatic malignancy principally affecting patients of pediatric age group. We present a case undifferentiated embryonal sarcoma of liver in a 1-year old female. She presented with complaints of abdominal distension and vomiting for 2 weeks. Ultrasonography showed grossly enlarged liver with multiple heterogenous lesions. Computed tomography revealed presence of large exophytic lesion of size 11.3 × 7 cm involving left lobe of liver. Ultrasound guided biopsy was performed, and specimen was sent for histopathological examination. On Microscopic examination undifferentiated round to spindle cells in myxoid background were seen. Immunohistochemistry revealed positivity for vimentin and AE1 thus proving undifferentiated embryonal sarcoma of liver. Diagnosis is often challenging because of overlapping epidemiological, clinical, radiological findings with those of other liver tumors.


Nisha Khanna, Shailee Mehta, Alok Ranjan, Biren Parikh, Dhaval Jetly and Vaibhavi H Dhimmar

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