Medical Case Reports

Thrombotic Microangiopathy in COVID-19 and its Association with Complement Classical Pathway

COVID-19 pandemic has affected the whole world in last 1 year with catastrophic effects. This virus has been commonly associated with thromboembolic tendency, resulting in pulmonary embolism, Cerebrovascular accidents, Myocardial infarctions and Acral Cyanosis. Acute kidney injury is also very common amongst patients with COVID-19 infection, mostly due to pre-renal AKI, Acute tubular necrosis or collapsing glomerulopathy. Renal injury due to thrombotic microangiopathy and cortical necrosis is not a common finding in COVID-19 infections. Here we are reporting a case of young female with Critical COVID Pneumonitis and Cytokine release syndrome, who developed AKI due severe TMA and cortical necrosis.

Author(s):

Javeria Chughtai* , Imtiaz Salman, Aamir Zunaira, Ahmad Shehzad, Mubarak Muhammed, Saeed Faiza, Alam Ashar, Memon Shoukat, TariqSobia

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