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Dorsolamide May Have a Role in Unoperable Diabetic Retinopathy

Aim: To assess the efficacy of long term use of dorzolamide in unoperable cases of diabetic retinopathy.
Method: A collection of 33 cases of diabetic patients, that are not amenable to have surgical treatment for any reason with advanced and late stages of retinopathy exposed to the effect of dorzolamide topically administered three times a day for life with a mean period of follow up from 2012 till the time of putting the results on papers. Meanwhile, those patients also received vitamins and antioxidants supplements plus follow up with medical consultant.
Results: All patients record satisfactory stationary outcome encouraging results after 3 months of continuous use of topical dorsolamide. Variable changes in visual acuity assessed but shows no significant improvement, however most of cases retain vision that is functionally accepted.
Discussion: Long term use of topical dorsolamide have several benefits through regulating activity of elevated level of enzymes, pH status correction, improving homeostasis, enhance cell metabolism and survival.
Conclusion: The outcome result may stimulate using topical CA inhibitors in other stages of diabetic retinopathy or even as a prophylaxis to ameliorate the progressive deterioration.


Maan A. Kitab*

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