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A Case of Hereditary Spherocytosis with Associated Hypersplenism

Hereditary spherocytosis is a less common blood disorder where the cytoskeleton of red blood cell is defective due to mutation in their structural proteins and consequently the cell becomes spherical and fragile and destructed earlier than their usual life span. The case was a 25 year old male who had been suffering from continuous lethargy, weakness and abdominal pain for 2 years. After thorough clinical and laboratory exams he had spherical red blood cells in peripheral blood film and elevated fragile osmotic test, therefore he diagnosed with hereditary spherocytosis. Hereditary spherocytosis an infrequent red blood cell disorder where the cells become round and easily destructed and osmotic fragile test helps for confirmed diagnosis


Fazel Rahim Wardak* , Nowshirwan Safi and Hedayatullah Hayat

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