Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis, is a rare form of vasculitis. In this disorder, small-sized blood vessels in the nose, sinuses, ears, lungs and kidneys become inflamed and damaged. Other areas may also be affected in some cases. It can also produce a type of inflammatory tissue known as a granuloma that's found around the blood vessels. Granulomas can destroy normal tissue. It is the result of inflammation within the tissues called granulomatous inflammation and blood vessel inflammation ("vasculitis"), which can damage organ systems.
Carmela Leone, Emanuele D’Amico, Nunzio Platania, Rosario Caltabiano, Mario Zappia, and Francesco Patti
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