Budd-Chiari Syndrome in a Patient with JAK-2 Mutation without Myeloprolifrative Disorder

A 41-year-old woman presented with right upper quadrant abdominal pain, found to have a primary buddchiari syndrome secondary to right hepatic vein thrombosis. Her thrombophilia workup revealed a JAK2 mutation is a setting of no signs of myeloproliferative disorders. JAK2V617F mutation could be a pro-coagulant to thrombosis even without myeloprolifrative disorders.


Mohammed Salhab, Daniel Ellis, Andrew Hsu and Bradley Switzer

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